• The most important outcomes (both benefits and harms)
• Size of these effects
• Certainty of this evidence

• Layers of information for drilling down from simple to complex
• Choice of viewing evidence as text, numbers or graphics
• Step-by-step visualizations that help explain results, including confidence intervals
• Interactive explanation of terms
• Interactive footnotes
• Responsive design (will automatically adapt to small screens or device displays)
• Available in different languages
• Available for test accuracy questions

• Template flexibility; can accommodate data from different kinds of reviews, including those without meta-analysis)
• Present different levels of baseline (control group) risk for each outcome
• Control over default display (e.g. which outcomes, what information about each outcome, which baseline risk are visible)
• Allowing producers to tailor their own template (for instance to rearrange the order of the columns, create a custom default presentation, or add organization logos)
• Templates for table production in different languages
• Automatic reminders to include information that is essential for understanding results (e.g. explanations about scales, about where estimates of baseline risk came from, and reasons for downgrading or upgrading the certainty of evidence)

• You can explore an example completed iSoF in GRADEpro and at http://isof.epistemonikos.org/#/finding/55ddb808352a506111abe4ea and for test accuracy questions here in GRADE database 

• The iSoF is supported in GRADE's DECIDE-supported software GRADEProGDT and by Epistemonikos at http://isof.epistemonikos.org/#/

Publications

• GRADE Guidelines: 16. GRADE evidence to decision frameworks for tests in clinical practice and public health. JCE 2016; 76: 89-98

• Decision-Making about Healthcare Related Tests and Diagnostic Strategies: User Testing of GRADE Evidence Tables. PLoS One. 2015 Oct 16;10(10):e0134553